CO—100 | Apply now to make the list!— APPLICATIONS OPEN
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CO—100 2026: America's Top 100 Small Businesses

Applications are open for this year's CO—100 awards program. Enter your business today for a chance to earn a spot on the list!

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

Click here to enrolll!

Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



Working Late? You’re Not Alone

You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

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START » STARTUP

How to Start a Contracting Business

Construction contracting businesses often have higher barriers to overcome when starting out. From licensing requirements to marketing strategies, here are some tips to help you get started.

Showcase: The CO—100 2025 Experience

Step inside our 2025 CO—100 event through a curated gallery of standout moments—from the high-energy gala to exclusive VIP experiences and everything in between.

Small Businesses Are Using AI—Here’s What’s Actually Working

According to a recent whitepaper from the U.S. Chamber of Commerce Foundation and Hiring Our Heroes, small businesses are using AI to save time, streamline operations, and improve productivity. Here’s what’s working, what’s holding businesses back, and how to get started.

How 3 (Very Different) Startups Landed on Target’s Shelves

How a wellness spray, a supplement brand, and a nail-care disruptor turned online momentum, solid customer reviews, and disciplined growth into coveted launches at Target.

START » STRATEGY

Must-Attend Events for Small Business Month

From local conferences to virtual webinars, these events offer small business owners the opportunity to network and learn through the month of May.

How Elevate Business Solutions Builds a Culture of Collaboration

CO—100 Honoree Elevate Business Solutions empowers entrepreneurs with flexible executive assistant and bookkeeping support while fostering a strong, values-driven team culture.

Sebring Design Build Rebuilt Its Remodeling Business in a New Market

CO—100 Honoree Sebring Design Build adapted to major change by rebuilding its remodeling firm in Tennessee while maintaining its reputation for craftsmanship and client care.

Scaling Startups Unpack Customer Acquisition and Retention Strategies Driving Growth

To fuel growth, Puzzles of Color, CAKE, and AMVital acquire and retain customers through PR, online marketplaces, partnerships, content, and education.

Luminary’s Cate Luzio on How to Build a Powerful Business Network

Cate Luzio, Founder of Luminary, shares how strong networks, customer-first thinking, and strategic growth decisions can help small businesses scale and succeed.

Founder of Wine Recommendations App CellarTracker Expands User Base by Supercharging Crowdsourced Content with AI

Former Microsoft Engineer Eric LeVine taps artificial intelligence to help wine drinkers learn from the trove of data he has from its 10 million collectors.