CO—100 | Apply now to make the list!— APPLICATIONS OPEN
Applications Open:

CO—100 2026

Our annual small business award program is now accepting applications for 2026. Apply today to earn your place on our list of America’s top small businesses!

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

Click here to enrolll!

Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



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You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

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Latest—

The Small Business Talent Advantage

Mike Morello, Chief Digital Officer at the U.S. Chamber of Commerce, and Dwayne Myers, Co-Owner & CEO of Dynamic Automotive and a 2025 CO—100 Top Small Business, discuss how small businesses can attract and retain top talent in today’s workforce.

From Passion Project To Category Leader: Josh Cellars' Founder On Building America's Number One Premium Wine Brand

Josh Wines founder Joseph Carr shares his origin story from growing up in upstate New York to founding one of the nation’s leading wine brands. Interviewed by CO— Senior Editorial Director Barbara Thau.

Talking Taxes: A Small Business Perspective

Kris Thiessen, Senior Partner, Tax and Advisory at Block Advisors shares how the One Big Beautiful Bill impacts small business taxes and what businesses can do to take advantage of the new legislation.

Cybersecurity Simplified: Practical Protection For Small Business

Matthew Eggers, Vice President, Cybersecurity Policy, Cyber, Space, and National Security Policy Division, U.S. Chamber of Commerce, interviews Lisa Plaggemier, Executive Director, National Cybersecurity Alliance, on the practical actions small businesses can take to protect their data and financial information at Small Business Day 2026.

Small Business Day 2026: A View from the Small Business Administration

U.S. Small Business Administration Deputy Administrator Bill Briggs gives an inside look at how small businesses are doing in 2026 and the programs available to them through the SBA. Interviewed by Tom Sullivan, Senior Vice President Small Business Policy, U.S. Chamber of Commerce.

Small Business Update: Special Edition — Small Business Day 2026

Neil Bradley​, U. S. Chamber of Commerce Chief Policy Officer shares his take on the economy, tariffs and the latest on how small businesses are using AI.

Founded 1927: The Colonnade Preserves Nearly a Century of Southern Dining Tradition in Atlanta

This longtime neighborhood restaurant has built its legacy on familiar food, loyal customers, and generational consistency.

How AI Is Speeding Up Decision-Making for Businesses

Companies from Walmart to Crayola are tapping AI to expedite everything from managing product returns to maximizing social media trends, imparting best practices for businesses large and small.

John Boos & Co. Turns Craftsmanship Into a 130-Year Legacy of Kitchen Innovation

What began with a single handcrafted block has grown into a globally trusted name in wood and stainless steel kitchen equipment.

Rehab 2 Perform Grows a Hybrid Physical Therapy and Training Model Across Maryland

What began as a single clinic has expanded into a statewide network focused on recovery, performance, and long-term health.