INTRODUCING: THE 2026 CO—100— See the Full List
Announcing:

The 2026 CO—100 List

The 2026 CO—100 recognizes 100 small businesses that exemplify growth, adaptability, community impact, and the entrepreneurial spirit that drives America forward.

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

Click here to enroll

Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



Working Late? You’re Not Alone

You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

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Latest—

How Joolies’ Founders Turned Dates From a Forgotten Fruit Into a Buzzy Better-for-You Brand

The company professes to be “changing the date-ing game” with memorable branding and line expansions into healthful energy snacks and candy alternatives.

How BaseCamp Is Turning the Hot Apparel Resale Market into a Franchise Model

The brothers behind Uptown Cheapskate and Kid to Kid helped turn a fragmented thrift industry into a $300 million franchise, proving secondhand clothing retail can scale like any other Main Street business.

Inside Talkspace's Plan to Make AI Therapy Safe—and Profitable

As millions turn to chatbots for mental health advice, the virtual therapy pioneer is betting its new AI guide and its acquisition by a major behavioral health operator will accelerate growth.

How Disruptor NATPAT Turned Insect Repellent Into a Multimillion-dollar Sticker Business

The startup behind kid-friendly insect repellent and wellness patches built a global business by solving problems at home first and continues to run the brand like a family operation.

Data Privacy Compliance Basics

The complex network of data privacy regulations means small business owners should have a thorough approach to protecting customer data.

Consumer Trends Small Business Owners Should Know

A new report suggests AI, health, experiences, and resourcefulness are driving today’s customers.

A Small Business Guide to Nondisclosure Agreements

A nondisclosure agreement can help protect your confidential business information and give you legal recourse if anyone shares valuable company secrets.

What Is EBITDA?

EBITDA is a metric commonly used to estimate a company's value. Here’s how to calculate EBITDA and when to use it.

How to Find Your Small Business Credit Score

Check your credit with one of the credit agencies to understand how well positioned your company is to get favorable interest rates.

RUN » FINANCE

What Are Net Payment Terms?

Net terms are a way to offer customers favorable billing terms, and they can help you manage your cash flow—when they’re set up properly.