CO—100 | Apply now to make the list!— APPLICATIONS OPEN
Human Resources:

7 Simple Ways to Retain Your Best Employees

Learn how you can keep your best employees engaged and reduce costly turnover that can reach up to twice an employee’s salary.

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

Click here to enrolll!

Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



Working Late? You’re Not Alone

You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

Sign Up
Latest—

Rehab 2 Perform Grows a Hybrid Physical Therapy and Training Model Across Maryland

What began as a single clinic has expanded into a statewide network focused on recovery, performance, and long-term health.

START » STARTUP

How to Start a Contracting Business

Construction contracting businesses often have higher barriers to overcome when starting out. From licensing requirements to marketing strategies, here are some tips to help you get started.

START » STRATEGY

Successful U.S. Manufacturing Businesses

Many companies continue to make popular products in the United States, including bicycles, clothing, and kitchen tools. Here are some you should know.

Showcase: The CO—100 2025 Experience

Step inside our 2025 CO—100 event through a curated gallery of standout moments—from the high-energy gala to exclusive VIP experiences and everything in between.

Small Businesses Are Using AI—Here’s What’s Actually Working

According to a recent whitepaper from the U.S. Chamber of Commerce Foundation and Hiring Our Heroes, small businesses are using AI to save time, streamline operations, and improve productivity. Here’s what’s working, what’s holding businesses back, and how to get started.

How 3 (Very Different) Startups Landed on Target’s Shelves

How a wellness spray, a supplement brand, and a nail-care disruptor turned online momentum, solid customer reviews, and disciplined growth into coveted launches at Target.

START » STRATEGY

Must-Attend Events for Small Business Month

From local conferences to virtual webinars, these events offer small business owners the opportunity to network and learn through the month of May.

How Elevate Business Solutions Builds a Culture of Collaboration

CO—100 Honoree Elevate Business Solutions empowers entrepreneurs with flexible executive assistant and bookkeeping support while fostering a strong, values-driven team culture.

Sebring Design Build Rebuilt Its Remodeling Business in a New Market

CO—100 Honoree Sebring Design Build adapted to major change by rebuilding its remodeling firm in Tennessee while maintaining its reputation for craftsmanship and client care.

Scaling Startups Unpack Customer Acquisition and Retention Strategies Driving Growth

To fuel growth, Puzzles of Color, CAKE, and AMVital acquire and retain customers through PR, online marketplaces, partnerships, content, and education.