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CO—100 2026: America's Top 100 Small Businesses

Applications are open for this year's CO—100 awards program. Enter your business today for a chance to earn a spot on the list!

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

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Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



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Latest—

3 Ways Small Businesses Evolve Marketing as They Grow

As small businesses grow, their marketing strategies must evolve too. Learn how to build visibility, connect with customers, and scale your brand with the right tools and resources.

Earth’s Groove: How Herbal Experimentation Turned Into a Wellness Brand 

Founder Layla Morgan transformed a personal interest in herbal wellness into a brand built on community, education, and accessible self-care.

Health-Focused Startups Built Devoted Communities and a National Retail Presence

From probiotics to oral care, three founders explain how community-first strategies turned trust, education, and culture into breakout retail growth at merchants from Target to Anthropologie in the crowded wellness space.

How to Recover From a ‘Creative Hangover’

Creativity is linked to positive well-being, but a new study suggests it can sometimes have negative effects.

How OLIPOP Scaled a Mission-Driven Brand Without Losing Its Authenticity

OLIPOP Co-Founder Ben Goodwin shares lessons on scaling with authenticity, building a mission-driven brand, and taking smart entrepreneurial risks.

5 Strategies to Prepare Your Small Business for AI-Powered Cyberattacks

AI tools are making cyberattacks faster, cheaper, and more sophisticated. Here’s how small businesses can strengthen their defenses without dramatically increasing their budgets.

Founded 1875: After Fire, Mulholland Grocery Rebuilds, Endures, and Remains a Community’s Cornerstone

When fire destroyed his family’s century-old grocery store, Tom Mulholland chose to rebuild, preserving his small Iowa town’s access to fresh food.

How the Founder of Mrs. Meyer’s Clean Day Disrupted the Household Cleaning Market

Monica Nassif speaks to CO— about how she took her eco-conscious cleaning products company from a startup to a household name brand before selling it when she was in her early 50s.

Chefman Founder on Building a $400 Million Business and AI as the Future of Automated Cooking Appliances

Ralph Newhouse expands from sleek, functional appliances to smart devices with digital connectivity.

How to Elevate Your Small Business with Print Marketing

From packaging to signage, well-designed printed materials can help your small business stand out. Learn more about five smart print marketing strategies you can try.