CO—100 | Apply now to make the list!— APPLICATIONS OPEN
Apply Today!

CO—100 2026: America's Top 100 Small Businesses

Applications are open for this year's CO—100 awards program. Enter your business today for a chance to earn a spot on the list!

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

Click here to enrolll!

Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



Working Late? You’re Not Alone

You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

Sign Up
Latest—

Choosing a PEO: A Guide to Finding a Professional Employer Organization

Explore affordable PEO services for small businesses and get expert tips on what to look for, from features to fees, and how to ensure a smooth onboarding process.

Starting your Next Chapter? Advice on Franchise Ownership Later in Life

In this edition of “Ask the Board,” Kevin Lewis, Franchise Owner at Apex Leadership Company, shares his advice for entrepreneurs who would like to jump on the franchise bandwagon later in life.

How Too Much Busy Work Harms Productivity and Engagement

More than half of U.S. workers spend much of their time on low-value tasks—leading to frustration, burnout, and lower productivity.

Global Flavor Trends Drive Snack Innovations

Indie brands are making over the snack aisle with an infusion of flavors, ingredients, and recipes from around the world.

Bookstores Tap Indie Vibe, Personalization, and Social Media to Romance Reading For Today’s Consumers

Despite doomsayer predictions, brick-and-mortar bookstores’ demise hasn’t come. In fact, local bookstores—and revived big-brand chains—are luring customers in with new incentives, merch, and cultivated communities.

Women’s Sporting Goods Boom for Hot Startups Like Moolah Kicks and Round 21

Companies tap into a fast-growing niche with apparel and merchandise for fans and players ranging from basketballs featuring the artwork of Jean-Michel Basquiat to sneakers engineered for women’s feet.

Grow Your Business Through Mentorship: A Science Entrepreneur's Top Tips

In this edition of “Ask the Board,” we feature Dr. Jonathan Scheiman, Co-founder and CEO of FitBiomics, a sports biotechnology company. Jonathan shares his valuable tips for entrepreneurs who want to leverage mentors to help them grow.

Build for Retention: Why Emotionally Intelligent Products Win in the Long Run

In this edition of “Ask the Board,” we feature Henry Costa, CEO and Founder of Glorify, a daily devotional and meditation app. Henry explains the value of emotionally intelligent products for entrepreneurs and small business owners.

Hiring Your First Employees? Tips to Ensure Success

In this edition of “Ask the Board,” we feature Daniel Ramsey, CEO and Founder of MyOutDesk, a virtual staffing company. Daniel shares his insights for how to find the best first employees for your venture.

RUN » BUSINESS FINANCING

How Are Small Business Investment Deals Structured?

Every deal is different, but here are some basics you need to know before approaching investors.