CO—100 | Apply now to make the list!— APPLICATIONS OPEN
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CO—100 2026: America's Top 100 Small Businesses

Applications are open for this year's CO—100 awards program. Enter your business today for a chance to earn a spot on the list!

Small Business bAIsics: AI Training for Business Growth

Our virtual and in-person AI training, developed with support from Google and in partnership with the U.S. Chamber of Commerce Foundation, is the gateway to understanding and applying artificial intelligence in practical, powerful ways at your business.

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Interested in a small business membership?

Find out how the U.S. Chamber of Commerce can help your company grow and thrive in today's rapidly-evolving business environment. Connect with our team to learn how a small business membership can benefit your bottom line and help you achieve your goals.



Working Late? You’re Not Alone

You’re short on time and busy putting out fires. Sign up for our newsletter, Midnight Oil, and find out what you need to know to adapt and thrive tomorrow.

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Find retirement plans for employees by exploring profit-sharing, SEP IRA, and 401(k) companies for employers.

How to Switch PEOs

Seamlessly transfer to a new PEO using an exit strategy and PEO transition checklist. Learn why companies leave and the steps for doing so.

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How to Calculate Profit

Profit is a simple, yet powerful calculation that tells you whether your business is viable in the long run.

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Is My Business Tax-Exempt?

Could your business qualify for tax-exempt status? Learn what it means to be tax-exempt and how to apply.

Digital Shelf Labels Light Up Big and Small Retailers' Bottom Lines

Technology facilitates faster price changes and aids online order pickers for merchants ranging from mega-retailer Walmart to local Tennessee grocery Tate Family Foods.

Debunking Startup Myths With the Founders of AppArmor

Defying conventional wisdom, the Sinkinson brothers built AppArmor, a SaaS public safety mobile app company, by bootstrapping and focusing on empathetic leadership to boost profitability.

Credit Card Processing Scams and Fraud

Learn how to recognize a merchant services scam and prevent payment fraud while protecting your business and customers.

How AI Can Help Small Businesses Prepare for Tax Season

Discover the benefits and limitations of artificial intelligence-powered tax preparation plus shortcuts and prompts you can leverage.

Lovesac’s Founder on How Its ‘Designed for Life’ Philosophy Will Fuel Growth

The furniture company that won big with its ‘Sactional’ couches is betting its ‘buy better, buy less’ message will make it a billion-dollar brand.

Small Business Insurance: What Coverage Do You Need?

There are many types of small business insurance available, but what do you really need? Here’s how to choose the best policies and provider for your business.